Hypertension (American Heart Association)

Title: Point-of-Care Placental Growth Factor for Predicting Adverse Outcomes in Sierra Leone

Authors: Kuhrt K., Cole R., M’Bayoh M., Mabula-Bwalya C., Hurrell A., Ridout A., Fernandez-Turienzo C., Seed P.T., Chappell L.C., Bramham K., Shennan A.H.,on behalf of the Pineapple Study Group

Short Description: This new open-access publication in Hypertension (American Heart Association) presents a prospective cohort study in Sierra Leone evaluating two whole-blood, point-of-care PlGF tests (including Lepzi® PLGF Test) for women with hypertension in pregnancy. Both tests demonstrated high rule-out performance for severe maternal and perinatal outcomes—supporting risk stratification and clinical decision-making in low-resource settings.

Journal: Hypertension (American Heart Association)

Reference: Hypertension. 2025;82:1719–1728.DOI:10.1161/HYPERTENSIONAHA.125.24526